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venous leg ulcers

Low dose aspirin and compression does not increase healing of VLU

Low dose aspirin does not increase healing of venous leg ulcers (VLU) when used in addition to effective compression, according to researchers from the University of Auckland, New Zealand. The study, funded by the New Zealand Health Research Council and conducted by researchers at the University's National Institute for Health Innovation, found 150mg aspirin a day in addition to compression bandaging did not increase venous ulcer healing.

ERVA: Endovenous ablation betters compression therapy

Early endovenous ablation of superficial venous reflux as an adjunct to compression therapy is associated with a shorter time to healing of venous leg ulcers than compression therapy alone, according to the firsts results from the Early Venous Reflux Ablation (EVRA) ulcer randomised controlled trial.

RSM’s Venous Forum issues leg ulcer guidance

The Royal Society of Medicine’s Venous Forum (UK) has issued a guidance document for the ‘Management of patients with Leg Ulcers, to ensure that all patients with leg ulceration are offered the most appropriate care. In the guidance document, the Venous Forum state that leg ulcers continue to cause great distress to patients, cost the NHS millions of pounds each year and the prevalence of leg ulcers is increasing.

'Unclear’ whether PMM treatments for healing VLU are beneficial

A Chochrane review examining evidence on the effects of treatments designed to lower the levels of protease in venous leg ulcers (VLUs) has found that the evidence from clinical trials is ‘unclear’ as to whether there is a benefit of 'protease-modulating matrix' (PMM) dressings on hard-to-heal VLUs, in conjunction with compression treatment, compared with other dressings.

Apligraf shows positive change in chronic wound's genomic profile

Apligraf, an FDA-approved bioengineered living-cell therapy from Organogenesis, has become the first wound-healing therapy to demonstrate a significant change in the genomic profile of a treated non-healing wound, according to new research published in the peer-reviewed journal Science Translational Medicine.

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